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Brain-Computer Interfaces

& Neuroprostheses
Virtual Integration Environment
 Abstract
Previous research has shown that closed-loop control of a neuroprosthetic system, where subjects can actuate an external device while receiving feedback, allows users to adaptively correct errors and improve the accuracy of control. In lieu of the availability of advanced mechanical limbs capable of high levels of dexterity, we employ the use of a Virtual Integration Environment (VIE) to facilitate dexterous closed-loop control of an upper-limb prosthesis.
 
Using the VIE, which is implemented in MATLAB's Simulink environment, neural recordings from different non-human primate subjects can be streamed into the system. Separate decoding filters can then independently decode an entire suite of dexterous movements in real-time, including individual finger movements, wrist rotation, and grasps. Real-time visual feedback is provided through actuation of a virtual prosthetic hand, which models the dynamics and kinematics of an actual mechanical limb. The VIE provides an important testbench for the testing and validation of various cortical decoding algorithms.
 
Neural activity is recorded from primates as they perform dexterous movements of the hand. Independently trained classifiers decode the movement type in real-time, and the decoded output is used to actuate the final prosthetic limb. In lieu of a mechanical dexterous limb, the VIE provides real-time feedback of a virtual prosthetic arm to facilitate dexterous closed-loop control of a prosthetic device.
 
Researchers
Vikram Aggarwal, MSE
Girish Singhal, MSE
 
Collaborators
Johns Hopkins Applied Physics Laboratory
 
Funding
Defense Advanced Project and Research Agency (DARPA) - contract N66001-06-C-8005
National Science and Engineering Research Council (NSERC)
 
Publications
Aggarwal V, Singhal G, MH Schieber, NV Thakor, Towards closed-loop decoding of dexterous hand movements using a Virtual Integration Environment, Conf Proc IEEE Eng Med Biol Soc, 1:1703-06, 2008
 
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