Thakor Lab YouTube page       VLSI & Instrumentation Potentiostat  Abstract   We have designed a 16-channel potentiostat for detection of electroactive neurotransmitters such as dopamine and nitric oxide. The chip was fabricated in AMI 0.5 μm CMOS process and can be interfaced to any sensor array. The core of the design is a first-order single bit delta-sigma modulator with programmable oversampling ratio. The modulation of feedback duty-cycle in modulator design enables choice of current range in accordance to magnitude and time constant of signal leading to current range that spans over six orders of magnitude and sensitivity up to picoamperes at hundred millisecond conversion time with power consumption of 300 μW. Sub Topics Potentiostat Neuropotential Interface Head-Mounted Imager RF Telemetry & Power Harvesting     Micrograph of the 16-channel wide range femtoampere sensitivity potentiostat along with in-vitro measurement of dopamine activity.   Researchers Kartikeya Murari, MSE Christian Sauer, MSE   Collaborators Gert Cauwenberghs, PhD - University of California, San Diego   Funding NIH R21MH065296   Publications Stanacevic M, Murari K, Rege A, Cauwenberghs G, Thakor N, VLSI Potenstiostat Array with Oversampling Gain Modulation for Wide-Range Neurotransmitter Sensing, IEEE Trans Biomed Circuits and Sys, 12(1):63-72, 2007 Murari K, Stanacevic M, Cauwenberghs G, Thakor NV, Integrated potentiostat for neurotransmitter sensing, IEEE Eng Med Biol Mag, 24(6):23-9, 2005   Go to Top         Copyright © 2008 JHU Neuroengineering & Biomedical Instrumentation Lab All rights reserved.